Subject(s)
COVID-19/therapy , Endoscopy, Gastrointestinal , Esophageal and Gastric Varices/therapy , Gastroenterologists , Gastrointestinal Hemorrhage/therapy , Hemostatic Techniques , Liver Cirrhosis, Alcoholic/therapy , Adult , COVID-19/complications , COVID-19/diagnosis , Clinical Decision-Making , Endoscopy, Gastrointestinal/adverse effects , Esophageal and Gastric Varices/diagnosis , Esophageal and Gastric Varices/etiology , Fatal Outcome , Gastrointestinal Hemorrhage/diagnosis , Gastrointestinal Hemorrhage/etiology , Humans , Ligation , Liver Cirrhosis, Alcoholic/complications , Liver Cirrhosis, Alcoholic/diagnosis , Male , Risk Assessment , Risk Factors , Treatment OutcomeABSTRACT
We report on a patient with coronavirus disease 2019 (COVID-19) and decompensated cirrhosis who experienced a favourable outcome of severe immune thrombocytopaenic purpura (ITP) after administration of intravenous immunoglobulin and high-dose dexamethasone. The present case suggests that it is reasonable to evoke ITP in case of profound thrombocytopaenia in a patient with COVID-19.
Subject(s)
Coronavirus Infections , Glucocorticoids/administration & dosage , Immunoglobulins, Intravenous/administration & dosage , Liver Cirrhosis, Alcoholic , Obesity , Pandemics , Pneumonia, Viral , Purpura, Thrombocytopenic, Idiopathic , Adult , Betacoronavirus/isolation & purification , COVID-19 , Comorbidity , Coronavirus Infections/diagnosis , Coronavirus Infections/epidemiology , Coronavirus Infections/physiopathology , Humans , Hypoxia/diagnosis , Hypoxia/etiology , Immunologic Factors/administration & dosage , Liver Cirrhosis, Alcoholic/diagnosis , Liver Cirrhosis, Alcoholic/epidemiology , Male , Obesity/diagnosis , Obesity/epidemiology , Oxygen Inhalation Therapy/methods , Pneumonia, Viral/diagnosis , Pneumonia, Viral/epidemiology , Pneumonia, Viral/physiopathology , Purpura, Thrombocytopenic, Idiopathic/diagnosis , Purpura, Thrombocytopenic, Idiopathic/etiology , Purpura, Thrombocytopenic, Idiopathic/physiopathology , Purpura, Thrombocytopenic, Idiopathic/therapy , Radiography, Thoracic/methods , SARS-CoV-2 , Tomography, X-Ray Computed/methods , Treatment OutcomeABSTRACT
The novel severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) is a highly infectious viral disease that predominantly causes respiratory symptoms. Elevated liver enzymes have been reported during the course of disease and appear to be common. We present a 56-year-old woman with a history of decompensated alcoholic cirrhosis who presented with abdominal pain, fever and diarrhoea and was found to have acute on chronic liver failure secondary to SARS-CoV-2 infection. The patient was treated with empiric antibiotic and supportive care with subsequent improvement.